COPPER-CATALYZED DOMINO CYCLIZATION OF ANILINES AND CYCLOBUTANONE OXIME: A SCALABLE AND VERSATILE ROUTE TO SPIROTETRAHYDROQUINOLINE DERIVATIVES

Copper-catalyzed domino cyclization of anilines and cyclobutanone oxime: a scalable and versatile route to spirotetrahydroquinoline derivatives

In this study, we report the copper-catalyzed synthesis of tetrahydroquinoline derivatives via a domino reaction of female galaxy skin aniline with cyclobutanone oxime.This method demonstrates a selective approach for generating bioactive tetrahydroquinoline scaffolds, which have broad applications in pharmaceutical chemistry.The reaction condition

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Erosivity of rainfall in Lages, Santa Catarina, Brazil

The erosive capacity of rainfall can be expressed by an index and knowing it allows recommendation of soil management and conservation practices to reduce water erosion.The objective of this study was to calculate various indices of rainfall erosivity in Lages, Santa Catarina, Brazil, identify the best one, and discover its temporal distribution.Th

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Dietary determinants of changes in waist circumference adjusted for body mass index - a proxy measure of visceral adiposity.

Given the recognized health effects of visceral fat, the understanding of how diet can modulate changes in the phenotype "waist circumference for a given body mass index (WC(BMI))", a proxy measure of visceral adiposity, is deemed necessary.Hence, the objective of the present study was to assess the association between stirrup extender western diet

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