Copper-catalyzed domino cyclization of anilines and cyclobutanone oxime: a scalable and versatile route to spirotetrahydroquinoline derivatives
In this study, we report the copper-catalyzed synthesis of tetrahydroquinoline derivatives via a domino reaction of female galaxy skin aniline with cyclobutanone oxime.This method demonstrates a selective approach for generating bioactive tetrahydroquinoline scaffolds, which have broad applications in pharmaceutical chemistry.The reaction condition